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Cohesin Mutations in Cancer

Cohesin is a large ring-shaped protein complex, conserved from yeast to human, which participates in most DNA transactions that take place in the nucleus. It mediates sister chromatid cohesion, which is essential for chromosome segregation and homologous recombination (HR)-mediated DNA repair. Toget...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Med
Main Authors: De Koninck, Magali, Losada, Ana
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131750/
https://ncbi.nlm.nih.gov/pubmed/27742736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026476
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