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Local cellular and cytokine cues in the spleen regulate in situ T cell receptor affinity as well as function and fate of CD8(+) T cells
T cells rapidly undergo contraction upon viral clearance, but how T cell function and fate are determined during this phase is unclear. During the contraction phase of an acute infection with lymphocytic choriomeningitis virus, we found that virus-specific CD8(+) T cells within the splenic red pulp...
Tallennettuna:
| Julkaisussa: | Immunity |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5131716/ https://ncbi.nlm.nih.gov/pubmed/27851926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.10.024 |
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