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THE INHIBITORY EFFECT OF PACLITAXEL ON (KV2.1) K(+) CURRENT IN H9c2 CELLS
Using the whole-cell voltage clamp technique, we investigated the effect of paclitaxel, an anticancer agent which promotes microtubule formation, on K(+) current in H9c2 cells originated from rat embryonic cardiac myocytes. Paclitaxel inhibited Kv2.1 voltage-dependent K(+) current (IKur) with ultra-...
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Publicado no: | Fukushima J Med Sci |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Fukushima Society of Medical Science
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5131599/ https://ncbi.nlm.nih.gov/pubmed/25994081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5387/fms.2014-34 |
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