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The histone deacetylase inhibitor, sodium butyrate, exhibits neuroprotective effects for ischemic stroke in middle-aged female rats

BACKGROUND: Sodium butyrate (NaB) is a histone deacetylase (HDAC) inhibitor exhibiting anti-inflammatory and neuroprotective effects in a rat ischemic model of stroke as well as a myocardial ischemia model. Although clinical evidence shows that older women are at higher risk for stroke occurrence an...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Park, Min Jung, Sohrabji, Farida
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131416/
https://ncbi.nlm.nih.gov/pubmed/27905989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0765-6
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