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The potential neuroprotective role of a histone deacetylase inhibitor, sodium butyrate, after neonatal hypoxia-ischemia

BACKGROUND: Histone deacetylase inhibitor (HDACi), sodium butyrate (SB), has been shown to be neuroprotective in adult brain injury models. Potential explanation for the inhibitor action involves among others reduced inflammation. We therefore anticipated that SB will provide a suitable option for b...

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Pubblicato in:J Neuroinflammation
Autori principali: Jaworska, Joanna, Ziemka-Nalecz, Malgorzata, Sypecka, Joanna, Zalewska, Teresa
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5303300/
https://ncbi.nlm.nih.gov/pubmed/28187734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0807-8
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