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Introduction of foreign genes into tissues of living mice by DNA-coated microprojectiles.

Foreign genes were expressed in liver and skin cells of live mice by using a new apparatus to accelerate DNA-coated microprojectiles into tissues. After introduction of a plasmid in which the firefly luciferase gene was controlled by the human beta-actin promoter, luciferase activity was detectable...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Williams, R S, Johnston, S A, Riedy, M, DeVit, M J, McElligott, S G, Sanford, J C
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1991
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51311/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2011582/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.7.2726
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