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Determinants of tRNA Recognition by the Radical SAM Enzyme RlmN

RlmN, a bacterial radical SAM methylating enzyme, has the unusual ability to modify two distinct types of RNA: 23S rRNA and tRNA. In rRNA, RlmN installs a methyl group at the C2 position of A2503 of 23S rRNA, while in tRNA the modification occurs at nucleotide A37, immediately adjacent to the antico...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Fitzsimmons, Christina M., Fujimori, Danica Galonić
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130265/
https://ncbi.nlm.nih.gov/pubmed/27902775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167298
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