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Heads, Shoulders, Elbows, Knees, and Toes: Modular Gdf5 Enhancers Control Different Joints in the Vertebrate Skeleton

Synovial joints are crucial for support and locomotion in vertebrates, and are the frequent site of serious skeletal defects and degenerative diseases in humans. Growth and differentiation factor 5 (Gdf5) is one of the earliest markers of joint formation, is required for normal joint development in...

詳細記述

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書誌詳細
出版年:PLoS Genet
主要な著者: Chen, Hao, Capellini, Terence D., Schoor, Michael, Mortlock, Doug P., Reddi, A. Hari, Kingsley, David M.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130176/
https://ncbi.nlm.nih.gov/pubmed/27902701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006454
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