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Heads, Shoulders, Elbows, Knees, and Toes: Modular Gdf5 Enhancers Control Different Joints in the Vertebrate Skeleton

Synovial joints are crucial for support and locomotion in vertebrates, and are the frequent site of serious skeletal defects and degenerative diseases in humans. Growth and differentiation factor 5 (Gdf5) is one of the earliest markers of joint formation, is required for normal joint development in...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Chen, Hao, Capellini, Terence D., Schoor, Michael, Mortlock, Doug P., Reddi, A. Hari, Kingsley, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130176/
https://ncbi.nlm.nih.gov/pubmed/27902701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006454
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