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Methylation of Breast Cancer Predisposition Genes in Early-Onset Breast Cancer: Australian Breast Cancer Family Registry

DNA methylation can mimic the effects of both germline and somatic mutations for cancer predisposition genes such as BRCA1 and p16(INK4a). Constitutional DNA methylation of the BRCA1 promoter has been well described and is associated with an increased risk of early-onset breast cancers that have BRC...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Scott, Cameron M., Joo, JiHoon Eric, O’Callaghan, Neil, Buchanan, Daniel D., Clendenning, Mark, Giles, Graham G., Hopper, John L., Wong, Ee Ming, Southey, Melissa C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130174/
https://ncbi.nlm.nih.gov/pubmed/27902704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165436
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