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Mosaic Disorders of the PI3K/PTEN/AKT/TSC/mTORC1 signaling pathway

Mosaicism is the presence of two or more genetically distinct cell lineages originating from a single zygote. The skin frequently marks mosaic conditions through migration patterns of a population of mutant cells during embryogenesis. Somatic mutations in genes of the PI3K/PTEN/AKT/TSC/mTORC1 signal...

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Publicat a:Dermatol Clin
Autors principals: Nathan, Neera, Keppler-Noreuil, Kim M., Biesecker, Leslie G., Moss, Joel, Darling, Thomas N.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130114/
https://ncbi.nlm.nih.gov/pubmed/27890237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.det.2016.07.001
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