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Constitutive Glycolytic Metabolism Supports CD8(+) T cell Effector Memory Differentiation During Viral Infection

Extensive metabolic changes accompany T cell activation including a switch to glycolytic energy production and increased biosynthesis. Recent studies suggest that subsequent return to reliance on oxidative phosphorylation and increasing spare respiratory capacity are essential for the differentiatio...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Phan, Anthony T., Doedens, Andrew L., Palazon, Asis, Tyrakis, Petros A., Cheung, Kitty P., Johnson, Randall S., Goldrath, Ananda W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130099/
https://ncbi.nlm.nih.gov/pubmed/27836431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.10.017
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