Identification of FRA-1 as a novel player in pancreatic cancer in cooperation with a MUC1: ERK signaling axis

The MUC1 glycoprotein is overexpressed and aberrantly glycosylated in >90% of pancreatic ductal adenocarcinoma cases and impacts tumor progression by initiating downstream signaling through phosphorylation of its cytoplasmic tail. Previous studies have demonstrated that MUC1 alters expression of...

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Udgivet i:Oncotarget
Main Authors: Hanson, Ryan L., Brown, Roger B., Steele, Maria M., Grandgenett, Paul M., Grunkemeyer, James A., Hollingsworth, Michael A.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129987/
https://ncbi.nlm.nih.gov/pubmed/27220889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9557
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