The chronological sequence of somatic mutations in early gastric carcinogenesis inferred from multiregion sequencing of gastric adenomas

Mutation profiles and intratumoral heterogeneity are not well understood for benign gastric adenomas, some of which progress into malignant gastric adenocarcinomas. In this study, we performed whole-exome sequencing of three microsatellite stable (MSS) and two microsatellite instability-high (MSI-H)...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lim, Chul-Hyun, Cho, Yu Kyung, Kim, Sang Woo, Choi, Myung-Gyu, Rhee, Je-Keun, Chung, Yeun-Jun, Lee, Sug-Hyung, Kim, Tae-Min
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129968/
https://ncbi.nlm.nih.gov/pubmed/27175599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9250
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