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IL-2 and IL-6 cooperate to enhance the generation of influenza-specific CD8 T cells responding to live influenza virus in aged mice and humans
An age-related decline in cytolytic activity has been described in CD8(+) T cells and we have previously shown that the poor CD8(+) effector T cell responses to influenza A/H3N2 challenge result from a decline in the proportion and function of these cytolytic T lymphocytes (CTL). Here, we describe t...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5129923/ https://ncbi.nlm.nih.gov/pubmed/27322555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10047 |
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