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Influenza vaccine-mediated protection in older adults: Impact of influenza infection, cytomegalovirus serostatus and vaccine dosage

Age-related changes in T-cell function are associated with a loss of influenza vaccine efficacy in older adults. Both antibody and cell-mediated immunity plays a prominent role in protecting older adults, particularly against the serious complications of influenza. High dose (HD) influenza vaccines...

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Bibliographic Details
Published in:Exp Gerontol
Main Authors: Merani, Shahzma, Kuchel, George A., Kleppinger, Alison, McElhaney, Janet E.
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871551/
https://ncbi.nlm.nih.gov/pubmed/28958701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2017.09.015
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