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Retinal Proteoglycans Act as Cellular Receptors for Basement Membrane Assembly to Control Astrocyte Migration and Angiogenesis

The basement membrane is crucial for cell polarity, adhesion and motility, but how it is assembled on cell surface remains unclear. Here, we find that ablation of glycosaminoglycan (GAG) side chains of proteoglycans in the neuroretina disrupts the retinal basement membrane, leading to arrested astro...

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Bibliografische gegevens
Gepubliceerd in:Cell Rep
Hoofdauteurs: Tao, Chenqi, Zhang, Xin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129871/
https://ncbi.nlm.nih.gov/pubmed/27829154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.035
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