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Retinal Proteoglycans Act as Cellular Receptors for Basement Membrane Assembly to Control Astrocyte Migration and Angiogenesis

The basement membrane is crucial for cell polarity, adhesion and motility, but how it is assembled on cell surface remains unclear. Here, we find that ablation of glycosaminoglycan (GAG) side chains of proteoglycans in the neuroretina disrupts the retinal basement membrane, leading to arrested astro...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Tao, Chenqi, Zhang, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129871/
https://ncbi.nlm.nih.gov/pubmed/27829154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.035
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