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Retinal Proteoglycans Act as Cellular Receptors for Basement Membrane Assembly to Control Astrocyte Migration and Angiogenesis
The basement membrane is crucial for cell polarity, adhesion and motility, but how it is assembled on cell surface remains unclear. Here, we find that ablation of glycosaminoglycan (GAG) side chains of proteoglycans in the neuroretina disrupts the retinal basement membrane, leading to arrested astro...
Guardat en:
| Publicat a: | Cell Rep |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5129871/ https://ncbi.nlm.nih.gov/pubmed/27829154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.035 |
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