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Iroquois homeobox transcription factor (Irx5) promotes G(1)/S-phase transition in vascular smooth muscle cells by CDK2-dependent activation

The Iroquois homeobox (Irx5) gene is essential in embryonic development and cardiac electrophysiology. Although recent studies have reported that IRX5 protein is involved in regulation of the cell cycle and apoptosis in prostate cancer cells, little is known about the role of IRX5 in the adult vascu...

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Detalles Bibliográficos
Publicado en:Am J Physiol Cell Physiol
Main Authors: Liu, Dong, Pattabiraman, Vaishnavi, Bacanamwo, Methode, Anderson, Leonard M.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129766/
https://ncbi.nlm.nih.gov/pubmed/27170637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00293.2015
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