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Intracellular ascorbate tightens the endothelial permeability barrier through Epac1 and the tubulin cytoskeleton
Vitamin C, or ascorbic acid, both tightens the endothelial permeability barrier in basal cells and also prevents barrier leak induced by inflammatory agents. Barrier tightening by ascorbate in basal endothelial cells requires nitric oxide derived from activation of nitric oxide synthase. Although as...
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| Publicado no: | Am J Physiol Cell Physiol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5129753/ https://ncbi.nlm.nih.gov/pubmed/27605450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00076.2016 |
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