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Nitric Oxide Mediates Tightening of the Endothelial Barrier by Ascorbic Acid

Vitamin C, or ascorbic acid, decreases paracellular endothelial permeability in a process that requires rearrangement of the actin cytoskeleton. To define the proximal mechanism of this effect, we tested whether it might involve enhanced generation and/or sparing of nitric oxide (NO) by the vitamin....

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Détails bibliographiques
Auteurs principaux: May, James M., Qu, Zhi-chao
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022079/
https://ncbi.nlm.nih.gov/pubmed/21156160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.12.046
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