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Characterizing the impact of sustained sulfadoxine/pyrimethamine use upon the Plasmodium falciparum population in Malawi

BACKGROUND: Malawi experienced prolonged use of sulfadoxine/pyrimethamine (SP) as the front-line anti-malarial drug, with early replacement of chloroquine and delayed introduction of artemisinin-based combination therapy. Extended use of SP, and its continued application in pregnancy is impacting th...

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Vydáno v:Malar J
Hlavní autoři: Ravenhall, Matt, Benavente, Ernest Diez, Mipando, Mwapatsa, Jensen, Anja T. R., Sutherland, Colin J., Roper, Cally, Sepúlveda, Nuno, Kwiatkowski, Dominic P., Montgomery, Jacqui, Phiri, Kamija S., Terlouw, Anja, Craig, Alister, Campino, Susana, Ocholla, Harold, Clark, Taane G.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129638/
https://ncbi.nlm.nih.gov/pubmed/27899115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-016-1634-6
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