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The role of PIM1/PIM2 kinases in tumors of the male reproductive system

The PIM family of serine/threonine kinases has three highly conserved isoforms (PIM1, PIM2 and PIM3). PIM proteins are regulated through transcription and stability by JAK/STAT pathways and are overexpressed in hematological malignancies and solid tumors. The PIM kinases possess weak oncogenic abili...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Jiménez-García, Manuel Pedro, Lucena-Cacace, Antonio, Robles-Frías, María José, Narlik-Grassow, Maja, Blanco-Aparicio, Carmen, Carnero, Amancio
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5128923/
https://ncbi.nlm.nih.gov/pubmed/27901106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38079
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