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The role of PIM1/PIM2 kinases in tumors of the male reproductive system
The PIM family of serine/threonine kinases has three highly conserved isoforms (PIM1, PIM2 and PIM3). PIM proteins are regulated through transcription and stability by JAK/STAT pathways and are overexpressed in hematological malignancies and solid tumors. The PIM kinases possess weak oncogenic abili...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5128923/ https://ncbi.nlm.nih.gov/pubmed/27901106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38079 |
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