Genetic Modeling of PIM Proteins in Cancer: Proviral Tagging and Cooperation with Oncogenes, Tumor Suppressor Genes, and Carcinogens

The PIM proteins, which were initially discovered as proviral insertion sites in Moloney-murine leukemia virus infection, are a family of highly homologous serine/threonine kinases that have been reported to be overexpressed in hematological malignancies and solid tumors. The PIM proteins have also...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Aguirre, Enara, Renner, Oliver, Narlik-Grassow, Maja, Blanco-Aparicio, Carmen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2014
Pynciau:
Oncology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030178/
https://ncbi.nlm.nih.gov/pubmed/24860787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00109
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