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Influenza A Virus Hemagglutinin Specific Antibodies Interfere with Virion Neuraminidase Activity Via Two Distinct Mechanisms
We studied the ability of monoclonal Abs (mAbs) recognizing the major hemagglutinin (HA) antigenic sites to inhibit neuraminidase (NA) cleavage of sialic acids on fetuin. We show that virion associated-NA activity in the enzyme linked lectin assay (ELLA) is largely dependent on HA-mediated attachmen...
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| Publicado no: | Virology |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5127735/ https://ncbi.nlm.nih.gov/pubmed/27825034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2016.10.024 |
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