Scaffold-mediated BMP-2 minicircle DNA delivery accelerated bone repair in a mouse critical-size calvarial defect model

Scaffold-mediated gene delivery holds great promise for tissue regeneration. However, previous attempts to induce bone regeneration using scaffold-mediated non-viral gene delivery rarely resulted in satisfactory healing. We report a novel platform with sustained release of minicircle DNA (MC) from P...

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Detalhes bibliográficos
Publicado no:J Biomed Mater Res A
Main Authors: Keeney, Michael, Chung, Michael T., Zielins, Elizabeth R., Paik, Kevin J., McArdle, Adrian, Morrison, Shane D., Ransom, Ryan C., Barbhaiya, Namrata, Atashroo, David, Jacobson, Gunilla, Zare, Richard N., Longaker, Michael T., Wan, Derrick C., Yang, Fan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127622/
https://ncbi.nlm.nih.gov/pubmed/27059085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.35735
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