Scaffold-mediated BMP-2 minicircle DNA delivery accelerated bone repair in a mouse critical-size calvarial defect model

Scaffold-mediated gene delivery holds great promise for tissue regeneration. However, previous attempts to induce bone regeneration using scaffold-mediated non-viral gene delivery rarely resulted in satisfactory healing. We report a novel platform with sustained release of minicircle DNA (MC) from P...

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Vydáno v:J Biomed Mater Res A
Hlavní autoři: Keeney, Michael, Chung, Michael T., Zielins, Elizabeth R., Paik, Kevin J., McArdle, Adrian, Morrison, Shane D., Ransom, Ryan C., Barbhaiya, Namrata, Atashroo, David, Jacobson, Gunilla, Zare, Richard N., Longaker, Michael T., Wan, Derrick C., Yang, Fan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127622/
https://ncbi.nlm.nih.gov/pubmed/27059085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.35735
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