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Systematic chemical-genetic and chemical-chemical interaction datasets for prediction of compound synergism

The network structure of biological systems suggests that effective therapeutic intervention may require combinations of agents that act synergistically. However, a dearth of systematic chemical combination datasets have limited the development of predictive algorithms for chemical synergism. Here,...

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Библиографические подробности
Опубликовано в: :Sci Data
Главные авторы: Wildenhain, Jan, Spitzer, Michaela, Dolma, Sonam, Jarvik, Nick, White, Rachel, Roy, Marcia, Griffiths, Emma, Bellows, David S., Wright, Gerard D., Tyers, Mike
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127411/
https://ncbi.nlm.nih.gov/pubmed/27874849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sdata.2016.95
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