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Reduced high-frequency motor neuron firing, EMG fractionation, and gait variability in awake walking ALS mice
Amyotrophic lateral sclerosis (ALS) is a lethal neurodegenerative disease prominently featuring motor neuron (MN) loss and paralysis. A recent study using whole-cell patch clamp recording of MNs in acute spinal cord slices from symptomatic adult ALS mice showed that the fastest firing MNs are prefer...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5127366/ https://ncbi.nlm.nih.gov/pubmed/27821773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616832113 |
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