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Emulating proton-induced conformational changes in the vesicular monoamine transporter VMAT2 by mutagenesis

Neurotransporters located in synaptic vesicles are essential for communication between nerve cells in a process mediated by neurotransmitters. Vesicular monoamine transporter (VMAT), a member of the largest superfamily of transporters, mediates transport of monoamines to synaptic vesicles and storag...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yaffe, Dana, Vergara-Jaque, Ariela, Forrest, Lucy R., Schuldiner, Shimon
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127352/
https://ncbi.nlm.nih.gov/pubmed/27821772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605162113
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