High-density array-CGH with targeted NGS unmask multiple noncontiguous minute deletions on chromosome 3p21 in mesothelioma

We used a custom-made comparative genomic hybridization array (aCGH; average probe interval 254 bp) to screen 33 malignant mesothelioma (MM) biopsies for somatic copy number loss throughout the 3p21 region (10.7 Mb) that harbors 251 genes, including BRCA1 (breast cancer 1)-associated protein 1 (BAP1...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Yoshikawa, Yoshie, Emi, Mitsuru, Hashimoto-Tamaoki, Tomoko, Ohmuraya, Masaki, Sato, Ayuko, Tsujimura, Tohru, Hasegawa, Seiki, Nakano, Takashi, Nasu, Masaki, Pastorino, Sandra, Szymiczek, Agata, Bononi, Angela, Tanji, Mika, Pagano, Ian, Gaudino, Giovanni, Napolitano, Andrea, Goparaju, Chandra, Pass, Harvey I., Yang, Haining, Carbone, Michele
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127333/
https://ncbi.nlm.nih.gov/pubmed/27834213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1612074113
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars