Protein aggregation as a cellular response to oxidative stress induced by heme and iron

Hemolytic diseases include a variety of conditions with diverse etiologies in which red blood cells are destroyed and large amounts of hemeproteins are released. Heme has been described as a potent proinflammatory molecule that is able to induce multiple innate immune responses, such as those trigge...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Vasconcellos, Luiz R. C., Dutra, Fabianno F., Siqueira, Mariana S., Paula-Neto, Heitor A., Dahan, Jennifer, Kiarely, Ellen, Carneiro, Leticia A. M., Bozza, Marcelo T., Travassos, Leonardo H.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127311/
https://ncbi.nlm.nih.gov/pubmed/27821769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608928113
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