Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neurons

Recent studies have pointed to protein S-nitrosylation as a critical regulator of cellular redox homeostasis. For example, S-nitrosylation of peroxiredoxin-2 (Prx2), a peroxidase widely expressed in mammalian neurons, inhibits both enzymatic activity and protective function against oxidative stress....

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Sunico, Carmen R., Sultan, Abdullah, Nakamura, Tomohiro, Dolatabadi, Nima, Parker, James, Shan, Bing, Han, Xuemei, Yates, John R., Masliah, Eliezer, Ambasudhan, Rajesh, Nakanishi, Nobuki, Lipton, Stuart A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2016
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PNAS Plus
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127299/
https://ncbi.nlm.nih.gov/pubmed/27821734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608784113
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