Growth Hormone Control of Hepatic Lipid Metabolism

In humans, low levels of growth hormone (GH) and its mediator, IGF-1, associate with hepatic lipid accumulation. In mice, congenital liver-specific ablation of the GH receptor (GHR) results in reductions in circulating IGF-1 and hepatic steatosis, associated with systemic insulin resistance. Due to...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Diabetes
Autori principali: Liu, Zhongbo, Cordoba-Chacon, Jose, Kineman, Rhonda D., Cronstein, Bruce N., Muzumdar, Radhika, Gong, Zhenwei, Werner, Haim, Yakar, Shoshana
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2016
Soggetti:
Metabolism
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127251/
https://ncbi.nlm.nih.gov/pubmed/27679560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0649
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