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Growth Hormone Control of Hepatic Lipid Metabolism
In humans, low levels of growth hormone (GH) and its mediator, IGF-1, associate with hepatic lipid accumulation. In mice, congenital liver-specific ablation of the GH receptor (GHR) results in reductions in circulating IGF-1 and hepatic steatosis, associated with systemic insulin resistance. Due to...
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| Publié dans: | Diabetes |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Diabetes Association
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5127251/ https://ncbi.nlm.nih.gov/pubmed/27679560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0649 |
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