Enhanced GLUT4-Dependent Glucose Transport Relieves Nutrient Stress in Obese Mice Through Changes in Lipid and Amino Acid Metabolism

Impaired GLUT4-dependent glucose uptake is a contributing factor in the development of whole-body insulin resistance in obese patients and obese animal models. Previously, we demonstrated that transgenic mice engineered to express the human GLUT4 gene under the control of the human GLUT4 promoter (i...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Gurley, Jami M., Ilkayeva, Olga, Jackson, Robert M., Griesel, Beth A., White, Phillip, Matsuzaki, Satochi, Qaisar, Rizwan, Van Remmen, Holly, Humphries, Kenneth M., Newgard, Christopher B., Olson, Ann Louise
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2016
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127250/
https://ncbi.nlm.nih.gov/pubmed/27679559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0709
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