Pathogens Inactivated by Low-Energy-Electron Irradiation Maintain Antigenic Properties and Induce Protective Immune Responses

Inactivated vaccines are commonly produced by incubating pathogens with chemicals such as formaldehyde or β-propiolactone. This is a time-consuming process, the inactivation efficiency displays high variability and extensive downstream procedures are often required. Moreover, application of chemical...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Fertey, Jasmin, Bayer, Lea, Grunwald, Thomas, Pohl, Alexandra, Beckmann, Jana, Gotzmann, Gaby, Casado, Javier Portillo, Schönfelder, Jessy, Rögner, Frank-Holm, Wetzel, Christiane, Thoma, Martin, Bailer, Susanne M., Hiller, Ekkehard, Rupp, Steffen, Ulbert, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127033/
https://ncbi.nlm.nih.gov/pubmed/27886076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8110319
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