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Diacylglycerol Kinases: Shaping Diacylglycerol and Phosphatidic Acid Gradients to Control Cell Polarity

Diacylglycerol kinases (DGKs) terminate diacylglycerol (DAG) signaling and promote phosphatidic acid (PA) production. Isoform specific regulation of DGKs activity and localization allows DGKs to shape the DAG and PA gradients. The capacity of DGKs to constrain the areas of DAG signaling is exemplifi...

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Detalles Bibliográficos
Publicado en:Front Cell Dev Biol
Main Authors: Baldanzi, Gianluca, Bettio, Valentina, Malacarne, Valeria, Graziani, Andrea
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126041/
https://ncbi.nlm.nih.gov/pubmed/27965956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2016.00140
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