Local pulsatile PTH delivery regenerates bone defect via enhanced bone remodeling in a cell-free scaffold

Parathyroid hormone (PTH) is currently the only FDA-approved anabolic drug to treat osteoporosis, and is systemically administered through daily injections. A new local pulsatile PTH delivery device was developed from biodegradable polymers to expand PTH’s application from osteoporosis treatment to...

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Bibliografske podrobnosti
izdano v:Biomaterials
Main Authors: Dang, Ming, Koh, Amy J., Jin, Xiaobing, McCauley, Laurie K., Ma, Peter X.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125900/
https://ncbi.nlm.nih.gov/pubmed/27835763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.10.049
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