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Preprogrammed long-term systemic pulsatile delivery of parathyroid hormone to strengthen bone

Parathyroid hormone (PTH) is the only FDA approved anabolic agent for the treatment of osteoporosis. The anabolic action of PTH depends on the mode of PTH adminstration. Pulsatile administration promotes bone formation, however continuous PTH exposure results in bone resorption. In addition, the the...

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Detalhes bibliográficos
Publicado no:Adv Healthc Mater
Main Authors: Dang, Ming, Koh, Amy J., Danciu, Theodora, McCauley, Laurie K., Ma, Peter X.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299037/
https://ncbi.nlm.nih.gov/pubmed/27930873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201600901
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