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DNA-reactive B cells in lupus
IgG anti-DNA antibodies are both diagnostic and pathogenic for systemic lupus erythematosus (SLE). They contribute to tissue inflammation through direct tissue binding and to systemic inflammation through activation of Toll-like receptors by nucleic acid-containing immune complexes. IgG DNA-reactive...
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| Pubblicato in: | Curr Opin Immunol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5125853/ https://ncbi.nlm.nih.gov/pubmed/27504587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2016.07.002 |
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