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Meta-analysis of the impact of thioprine S-methyltransferase polymorphisms on the tolerable 6-mercaptopurine dose considering initial dose and ethnic difference

A meta-analysis was conducted to decide whether to reduce an initial 6-mercaptopurine (6-MP) dose in TPMT heterozygote in the case of an initial 6-MP dose of <75 mg/m(2)/d and to compare the tolerable 6-MP dose among different ethnic groups. The study was undertaken according to Preferred Reporti...

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Bibliografiske detaljer
Udgivet i:Onco Targets Ther
Main Authors: Kim, Myeong Gyu, Ko, Minoh, Kim, In-Wha, Oh, Jung Mi
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125793/
https://ncbi.nlm.nih.gov/pubmed/27920553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S110800
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