Azidothymidine Sensitizes Primary Effusion Lymphoma Cells to Kaposi Sarcoma-Associated Herpesvirus-Specific CD4+ T Cell Control and Inhibits vIRF3 Function

Kaposi sarcoma-associated herpesvirus (KSHV) is linked with the development of Kaposi sarcoma and the B lymphocyte disorders primary effusion lymphoma (PEL) and multi-centric Castleman disease. T cell immunity limits KSHV infection and disease, however the virus employs multiple mechanisms to inhibi...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Williamson, Samantha J., Nicol, Samantha M., Stürzl, Michael, Sabbah, Shereen, Hislop, Andrew D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125715/
https://ncbi.nlm.nih.gov/pubmed/27893813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006042
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