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Simulating Next-Generation Sequencing Datasets from Empirical Mutation and Sequencing Models

An obstacle to validating and benchmarking methods for genome analysis is that there are few reference datasets available for which the “ground truth” about the mutational landscape of the sample genome is known and fully validated. Additionally, the free and public availability of real human genome...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Stephens, Zachary D., Hudson, Matthew E., Mainzer, Liudmila S., Taschuk, Morgan, Weber, Matthew R., Iyer, Ravishankar K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125660/
https://ncbi.nlm.nih.gov/pubmed/27893777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167047
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