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Identification of a Key Cholesterol Binding Enhancement Motif in Translocator Protein 18 kDa
Translocator protein 18 kDa (TSPO) in the mitochondrial outer membrane has been implicated in cholesterol transport regulating steroidogenesis. A human single polymorphism associated with anxiety disorders (A147T) and reduced pregnenolone production is adjacent to TSPO’s cholesterol binding motif. I...
Shranjeno v:
| izdano v: | Biochemistry |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5125615/ https://ncbi.nlm.nih.gov/pubmed/25635829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5015453 |
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