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Salvianolic Acid B Alleviates Heart Failure by Inactivating ERK1/2/GATA4 Signaling Pathway after Pressure Overload in Mice

BACKGROUND: Heart failure(HF) is a dangerous disease that affects millions of patients. Radix Salvia is widely used in Chinese clinics to treat heart diseases. Salvianolic acid B(SalB) is the major active component of Radix Salvia. This study investigated the mechanisms of action and effects of SalB...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yu, Juan, Chen, Renshan, Tan, Yafang, Wu, Jiashin, Qi, Jianyong, Zhang, Minzhou, Gu, Weiwang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125602/
https://ncbi.nlm.nih.gov/pubmed/27893819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166560
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