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Virus-Mediated Alterations in miRNA Factors and Degradation of Viral miRNAs by MCPIP1
Kaposi’s sarcoma-associated herpesvirus (KSHV), the causative agent of Kaposi’s sarcoma, encodes 25 mature viral miRNAs. MCP-1-induced protein-1 (MCPIP1), a critical regulator of immune homeostasis, has been shown to suppress miRNA biosynthesis via cleavage of precursor miRNAs through its RNase doma...
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| Publicado no: | PLoS Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5125562/ https://ncbi.nlm.nih.gov/pubmed/27893764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2000998 |
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