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Viral microRNAs Target a Gene Network, Inhibit STAT Activation, and Suppress Interferon Responses

Kaposi’s sarcoma-associated herpesvirus (KSHV) encodes 12 pre-microRNAs during latency that are processed to yield ~25 mature microRNAs (miRNAs). We were interested in identifying cellular networks that were targeted by KSHV-miRNAs and employed network building strategies using validated KSHV miRNA...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Ramalingam, Dhivya, Ziegelbauer, Joseph M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244407/
https://ncbi.nlm.nih.gov/pubmed/28102325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40813
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