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α-Ketoglutarate dehydrogenase complex moonlighting: ROS signalling added to the list
Mitochondrial dysfunctions that occur in parallel to an exacerbated production of reactive oxygen species (ROS) affect energy metabolism in neurodegenerative disorders. The activity of the mitochondrial metabolic tricarboxylic acid (TCA) cycle enzyme 2-oxoglutarate dehydrogenase complex (KGDHC) is a...
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| Udgivet i: | J Neurochem |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5125520/ https://ncbi.nlm.nih.gov/pubmed/27882614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13862 |
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