Analysis of Dominant HIV Quasispecies Suggests Independent Viral Evolution Within Spinal Granulomas Coinfected with Mycobacterium tuberculosis and HIV-1 Subtype C

Extrapulmonary tuberculosis (TB) is a significant public health challenge in South Africa and worldwide, largely fuelled by the HIV epidemic. In spinal TB, Mycobacteria infect the spinal column without dissemination to the spinal cord. The immune microenvironment, target cell characteristics, and ot...

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Enregistré dans:
Détails bibliographiques
Publié dans:AIDS Res Hum Retroviruses
Auteurs principaux: Danaviah, Sivapragashini, de Oliveira, Tulio, Gordon, Michelle, Govender, Shunmugam, Chelule, Paul, Pillay, Sureshnee, Naicker, Thajasvarie, Cassol, Sharon, Ndung'u, Thumbi
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2016
Sujets:
Pathogenesis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125288/
https://ncbi.nlm.nih.gov/pubmed/26564424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2015.0189
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